Dexamethasone Caplet 0.5 mg, each caplet contains : Dexamethasone 0.5 mg.



Dexamethasone with active ingredient Dexamethasone is available as caplet 0.5 mg.



  • Primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcemia caused by cancer. 
  • Perennial rhinitis allergic, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, drug hypersensitivity reactions. 
  • Eye diseases due to inflammation or allergies, and not caused by a virus. 
  • As adjunctive therapy for short-term administration as in : Psoriatic arthritis, rheumatoid arthritis, rheumatoid arthritis “Juvenile”. 
  • Systemic Lupus Erythematosus (SLE), acute rheumatic carditis. 
  • Pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme (“Steven’s-Johnson syndrome”). 
  • Sarcoidosis. 
  • Cerebral edema. 
  • The effect for the type of vasogenic edema as a result of brain tumors, particularly metastases and glioblastoma. 
  • It may be helpful to : Idiopathic hemolytic anemia and autoimmune. 
  • Subacute hepatic necrosis, autoimmune chronic active hepatitis.



Adult :

Initial dose variable : 0.75 – 9 mg/day, 2 – 4 times daily or depending on the severity of the disease.

Mild disease : < 0.75 mg.

Severe disease : > 9 mg.



  • Systemic fungal infections. 
  • Ocular herpes simplex.
  • Patients who are sensitive to the drug and its components.



  • Sensitivity with infection in patients who received corticosteroids is not specific to a particular bacterial or fungal pathogens. When an infection occur the dose is maintained or increased and best treatment should be done against the infection. 
  • Long-term use of corticosteroids may result in subcapsular cataract pasterior, glaucoma with possible damage of the optic nerves and may enhance the secondary ocular infections due to fungi and viruses. 
  • Corticosteroids is not recommended for the first trimester pregnant women because the possibility of newborn babies suffering from symptoms of hypoadrenalism. 
  • Not recommended use in lactating women because the possibility of corticosteroids are secreted into breast milk. 
  • Secondary adrenocortical insufficiency due to the use of these drugs may be reduced by lowering the dose gradually. 
  • Coadministration Acetosal with corticosteroids is not recommended in patients with hypoprothrombinemia. 
  • Administration of these drugs can suppress the clinical symptoms of an infectious disease. 
  • Long-term use can lower the body’s immunity to infectious diseases. 
  • Corticosteroids is not recommended in patients with nonspecific ulcerative colitis, if there is a tendency perforation, abscess and other pyogenic infection, diverticulitis, fresh intestinal anastomoses, peptic ulcer, renal insufficiency, hypertension, osteoporosis, myasthenia gravis. 
  • Not recommended for children under 6 years old, carefully observe the children and babies who use corticosteroids in the long term to the growth and development of children. 
  • Administration of corticosteroids in patients with hypothyroid and cirrhosis may increase corticosteroids effects. 
  • Use with caution of these corticosteroids in patients with diabetes, because it can increase gluconeogenesis and reduced insulin sensitivity.



  • Antibacterial : Rifampicin accelerates corticosteroids metabolism. 
  • Antidiabetic : Antagonists through hypoglycemia effects. 
  • Antiepileptic : Carbamazepine, Phenobarbitone, Phenytoin and Pirimidone accelerate the metabolism through hypotensive effect. 
  • Antihipertensive : Antagonism through hypotensive effect.
  • Barbiturates : Accelerate corticosteroids metabolism. 
  • Diuretics : Antagonism to the effects of Acetazolamide diuretics, diuretics loop and Thiazide increase the risk of hypokalemia. 
  • Hormone antagonists : Aminoglutetimide accelerates Dexamethasone metabolism. 
  • Ulcer healing drug : Carbenoxolone increase the risk of hypoglycemia.



  • Musculoskeletal : Muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, pathologic fractures of long bones and osteonecrosis. 
  • Gastrointestinal tract : Peptic ulcer with possible perforation and hemorrhage, pancreatitis, abdominal distention and ulcerative esophagus. 
  • Dermatology : Impaired wound healing, thin fragile skin, facial erythema and increased sweating. 
  • Nervous system : Convulsions, increased intracranial pressure with papille edema (“pseudo tumor”), vertigo and headaches. 
  • Fluid and electrolyte disturbances : Sodium and fluid retention (edema) are rarely occur because only few have mineralocorticoid effect. This edema may occur in patients with impaired glomerular speed. 
  • Hypokalemia, hypertension and congenital heart failure. 
  • Endocrine : Menstrual irregularities, growth suppression in children of secondary adrenal insufficiency, especially in times of stress such as trauma and surgery. 
  • Carbohydrate and fat metabolism : This steroid use in diabetics can lead to increased gluconeogenesis and reduced sensitivity by insulin. In normal patients, carbohydrates and fats metabolism are not affected. 
  • Ophtalmic : Posterior subcapsular cataracts, sometimes increased intraocular pressure, glaucoma, and exophthalmos. 
  • Metabolic : Negative nitrogen balance due to protein catabolism. 
  • Hypersensitivity reactions : Anaphylactic reactions are rare.



Dexamethasone Caplet 0.5 mg                Box, 10 blisters @ 10 caplets        Reg. No. GKL0302334010A1







Manufactured by :


Sidoarjo – Indonesia